Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hypoglycemia and Glucagon01:15

Hypoglycemia and Glucagon

497
Without prolonged fasting, healthy individuals maintain blood glucose levels above 3.5 mM due to a well-adapted neuroendocrine counterregulatory system that effectively prevents acute hypoglycemia, a potentially life-threatening condition. The primary clinical scenarios for hypoglycemia encompass diabetes treatment, inappropriate production of endogenous insulin or insulin-like substances by tumors, and the use of glucose-lowering agents in non-diabetic individuals. Notably, hypoglycemia in the...
497
Diabetes: Symptoms, Diagnosis, and Complications01:15

Diabetes: Symptoms, Diagnosis, and Complications

1.4K
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
1.4K
Diabetes Mellitus: Overview and Type I Subtype01:22

Diabetes Mellitus: Overview and Type I Subtype

4.1K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
4.1K
Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

2.3K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
2.3K
Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

3.6K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
3.6K
Acute Pancreatitis II: Clinical Manifestations and Management01:30

Acute Pancreatitis II: Clinical Manifestations and Management

354
Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
354

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Two Patients With Extremely Long Type 1 Diabetes Duration With Very Few Complications and Remaining Insulin Secretion.

Clinical case reports·2026
Same author

Concurrent hepatic adenomatosis and hemangiomatosis in a patient with HNF1A MODY.

BMJ case reports·2025
Same author

Severe and Intractable Hypokalemia in a Patient With New-onset Type 1 Diabetes and COVID-19 Infection.

JCEM case reports·2025
Same author

Cognitive dysfunction in diabetes - the 'forgotten' diabetes complication: a narrative review.

Scandinavian journal of primary health care·2025
Same author

A Rare Case of Testosterone-Producing Non-Seminoma Germ-Cell Testicular Cancer.

JCEM case reports·2024
Same author

Ephemeral Diabetes After COVID-19 Vaccination.

JCEM case reports·2024
Same journal

A Biologically Dominant Trophoblastic Component Guiding Neoadjuvant EMA/CO in Endometrial Carcinoma: A Clinical Case Report.

Clinical case reports·2026
Same journal

Could Fabry Disease Cause Giant Coronary Aneurysms in a 7-Month-Old Infant: A Case Report.

Clinical case reports·2026
Same journal

Correction to "Loss of Consciousness in a Child Following Accidental Ingestion of Brimonidine Ointment: A Case Report".

Clinical case reports·2026
Same journal

Simultaneous Transvenous Lead Extraction and Intra-Operative Epicardial Extravascular Defibrillator (EV-ICD) Implantation During Tricuspid Valve Replacement.

Clinical case reports·2026
Same journal

Successful Surgical Management of Chronic Subdural Hematoma in a Patient With Severe Thrombocytopenia due to Aplastic Anemia: A Case Report.

Clinical case reports·2026
Same journal

Appendix Mucinous Neoplasm.

Clinical case reports·2026
See all related articles

Related Experiment Video

Updated: Nov 3, 2025

A Mouse Model of Hemorrhagic Transformation Induced by Acute Hyperglycemia Combined with Transient Focal Ischemia
09:35

A Mouse Model of Hemorrhagic Transformation Induced by Acute Hyperglycemia Combined with Transient Focal Ischemia

Published on: November 15, 2024

640

Hemiballismus in hyperglycemia.

Agnes Kataja Knight1, Peter Magnusson2,3, Åke Sjöholm2,4,5

  • 1Department of Anesthesiology Hudiksvall Hospital Hudiksvall Sweden.

Clinical Case Reports
|June 4, 2021
PubMed
Summary
This summary is machine-generated.

Hyperglycemia can cause acute brain lesions in diabetic patients. This case highlights reversible hemichoreic dyskinesia and basal ganglia changes in hyperosmolar non-ketotic syndrome.

Keywords:
diabeteshemiballismushemichoreahyperosmolar non‐ketotic syndrome

More Related Videos

Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes
07:22

Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes

Published on: March 7, 2025

477
Osmotic Minipump Implantation for Increasing Glucose Concentration in Mouse Cerebrospinal Fluid
06:21

Osmotic Minipump Implantation for Increasing Glucose Concentration in Mouse Cerebrospinal Fluid

Published on: April 7, 2023

1.8K

Related Experiment Videos

Last Updated: Nov 3, 2025

A Mouse Model of Hemorrhagic Transformation Induced by Acute Hyperglycemia Combined with Transient Focal Ischemia
09:35

A Mouse Model of Hemorrhagic Transformation Induced by Acute Hyperglycemia Combined with Transient Focal Ischemia

Published on: November 15, 2024

640
Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes
07:22

Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes

Published on: March 7, 2025

477
Osmotic Minipump Implantation for Increasing Glucose Concentration in Mouse Cerebrospinal Fluid
06:21

Osmotic Minipump Implantation for Increasing Glucose Concentration in Mouse Cerebrospinal Fluid

Published on: April 7, 2023

1.8K

Area of Science:

  • Neurology
  • Endocrinology
  • Metabolic Disorders

Background:

  • Diabetes mellitus can lead to both acute and chronic central nervous system (CNS) complications.
  • Hyperglycemia, a hallmark of uncontrolled diabetes, is increasingly recognized to precipitate neurological deficits.

Observation:

  • A case of hyperosmolar non-ketotic syndrome (HNS) presented with acute neurological symptoms.
  • The patient exhibited hemichoreic dyskinesia, characterized by involuntary, irregular, and jerky movements.

Findings:

  • Morphological changes were observed in the basal ganglia, a key area for motor control.
  • The neurological deficits, including hemichoreic dyskinesia, were found to be reversible upon correction of hyperglycemia.

Implications:

  • This case underscores the potential for acute, reversible CNS lesions in the context of severe hyperglycemia.
  • Highlights the importance of recognizing and managing HNS to prevent potentially lasting neurological damage.
  • Suggests that basal ganglia are susceptible to acute morphological changes during hyperosmolar states.