Anti-COVID-19 measurements for hidradenitis suppurativa patients

Evangelos J Giamarellos-Bourboulis1,2, Vincenzo Bettoli1,3, Gregor B E Jemec1,4,5

  • 1European Hidradenitis Suppurativa Foundation e.V., Dessau, Germany.

Insights

Patients with hidradenitis suppurativa (HS) appear to have a low incidence of COVID-19, and biological treatments do not seem to increase susceptibility. HS patients can be vaccinated against SARS-CoV-2, with those having metabolic syndrome prioritized.

Area of Science:

  • Immunology
  • Dermatology
  • Infectious Diseases

Background:

  • The incidence of COVID-19 in patients with inflammatory bowel and skin diseases on biologicals is low.
  • Preliminary evidence suggests hidradenitis suppurativa (HS) does not increase COVID-19 susceptibility, and biological treatments may not negatively alter this risk.
  • Some biological modifiers are being explored for COVID-19 management, potentially benefiting HS patients.

Framework:

  • Consensus statement from European Hidradenitis Suppurativa Foundation e.V. experts on anti-COVID-19 measures for HS patients.
  • Recommendations based on available scientific knowledge regarding COVID-19 and HS.
  • Consideration of vaccination strategies for HS patients, including those with metabolic syndrome.

Implementation:

  • HS patients are recommended for SARS-CoV-2 vaccination.
  • Patients with metabolic syndrome and HS are identified as a high-risk group requiring timely vaccination.
  • HS patients on adalimumab can receive non-living virus SARS-CoV-2 vaccines, with a potential for suboptimal immune response.

Implications:

  • HS patients can be safely vaccinated against COVID-19.
  • Metabolic syndrome in HS patients necessitates prioritized vaccination.
  • Dermatologists should exercise discretion in managing biological treatments alongside vaccination.

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