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Updated: Nov 3, 2025
Preparation of Functional Silica Using a Bioinspired Method
Published on: August 1, 2018
Preparation of thermosensitive buprofezin-loaded mesoporous silica nanoparticles by the sol-gel method and their
Jinghan Yang1, Jianguo Feng1, Kangli He1
1School of Horticulture and Plant Protection, Yangzhou University, Yangzhou, China.
Background:
Environmental stimuli-responsive release is one important way to reduce the dosage of pesticide, increase the usage efficiency and improve environmental compatibility.
Results:
On this basis, we synthesized mesoporous silica nanoparticles (MSNs) and modified them to develop a thermosensitive pesticide controlled release formulation (CRF). In this study, MSNs prepared by the sol-gel method were used as the core, poly (N-IsoPropylAcrylaMide) [P (NIPAM-MAA)] was used as the shell, and buprofezin (Bup) was loaded by adsorption. The prepared Bup@MSNs@P(NIPAM-MAA) could effectively prevent the degradation of buprofezin under UV light and exhibited excellent adhesion to rice leaves. The bioassay results showed that the mortality of Nilaparvata lugens (Stål) treated by Bup@MSNs@P(NIPAM-MAA) was positively correlated with temperature, resulting mainly from the change of release amount of buprofezin caused by temperature variation. Bup@MSNs@P(NIPAM-MAA) had long duration (20 days) for controlling N. lugens, and did not hinder the growth of rice. Meanwhile, Bup@MSNs@P(NIPAM-MAA) had low toxicity to zebrafish and human pneumonocyte BEAS-2B cells.
Conclusion:
This novel thermosensitive pesticide CRF can be applied widely to other insecticides, thus greatly promoting the development of intelligent pesticide formulations. © 2021 Society of Chemical Industry.
