Related Experiment Video

Updated: Nov 3, 2025

Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
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Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure

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Prognostic value of serum bilirubin in patients with heart failure: A protocol for a systematic review and

Huan Wang1, Qiulei Jia2, Jingjing Shi2,3

  • 1Department of Cardiology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences.

Medicine
|June 4, 2021
PubMed

Insights

This study evaluates bilirubin

Area of Science:

  • Cardiology
  • Biomarkers
  • Clinical Prognosis

Background:

  • Heart failure (HF) is a critical condition often associated with elevated serum bilirubin.
  • The predictive role of bilirubin in HF prognosis remains unclear.

Purpose of the Study:

  • To systematically evaluate the predictive value of bilirubin for heart failure prognosis.
  • To clarify the association between bilirubin levels and outcomes in HF patients.

Main Methods:

  • Comprehensive systematic review and meta-analysis.
  • Searched major electronic databases (Medline, Embase, Web of Science, etc.).
  • Utilized Review Manager and STATA for data analysis.

Main Results:

  • The study will present synthesized evidence on bilirubin's predictive value in HF.
  • Results will systematically reveal the relationship between bilirubin and HF prognosis.

Conclusions:

  • Bilirubin levels may impact heart failure patient outcomes.
  • Findings aim to guide clinicians in monitoring bilirubin for early intervention in HF.
Abstract

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