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Candida pyelonephritis complicated by fungaemia in obstructive uropathy
1Department of Medicine, Medical College of Wisconsin, Milwaukee.
Abstract:
Fungal pyelonephritis caused by Candida species and Torulopsis without evidence of systemic organ involvement is uncommon. Most reported cases have been in diabetic females or in patients on immunosuppressive drugs. We report 3 cases of elderly men who had fungal pyelonephritis presumed secondary to obstructive uropathy. All subsequently developed fungaemia. Two were managed successfully with percutaneous or ureteric stents and systemic antifungal therapy; the third died despite systemic amphotericin B.
Insights
Fungal pyelonephritis is rare, especially in elderly men without systemic disease. Obstructive uropathy may predispose to this infection, leading to fungemia, with varied treatment outcomes.
Area of Science:
- Nephrology
- Mycology
- Infectious Diseases
Background:
- Fungal pyelonephritis, particularly from Candida and Torulopsis, is uncommon.
- Typically affects diabetic females or immunosuppressed patients.
- This study focuses on elderly males with obstructive uropathy.