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Updated: Nov 3, 2025

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Update on management of atrial fibrillation in heart failure: a focus on ablation
Bart A Mulder1, Michiel Rienstra2, Isabelle C Van Gelder2
1Department of Cardiology, University Medical Center Groningen, Groningen, The Netherlands b.a.mulder@umcg.nl.
Insights
Atrial fibrillation (AF) in heart failure patients requires managing symptoms and reducing risks. Catheter ablation shows promise for improving outcomes in this complex population.
Area of Science:
- Cardiology
- Electrophysiology
- Heart Failure Management
Background:
- Atrial fibrillation (AF) incidence is rising, frequently co-occurring with heart failure (HF).
- Managing AF in HF patients aims to alleviate symptoms and prevent thromboembolism and HF exacerbation.
Purpose of the Study:
- To review current literature on treating atrial fibrillation in heart failure patients.
- To critically evaluate catheter ablation studies in this patient group.
- To explore patient selection strategies for optimizing outcomes.
Main Methods:
- Review of existing literature on AF and HF treatment strategies.
- Analysis of early rate versus rhythm control studies.
- Evaluation of catheter ablation trials, including larger post-hoc analyses.
Main Results:
- Rate and rhythm control strategies are central to AF management in HF.
- Catheter ablation has demonstrated efficacy in patients with and without overt heart failure.
- Optimal treatment of underlying conditions and risk factors is crucial.
Conclusions:
- AF management in HF requires a multi-faceted approach addressing symptoms, risks, and comorbidities.
- Catheter ablation is a viable option for select HF patients with AF.
- Future research should focus on refining patient selection criteria for ablation to maximize benefits.
Abstract:
Atrial fibrillation is increasingly encountered in patients with heart failure. Both diseases have seen tremendous rises in incidence in recent years. In general, the treatment of atrial fibrillation is focused on relieving patients from atrial fibrillation-related symptoms and risk reduction for thromboembolism and the occurrence or worsening of heart failure. Symptomatic relief may be accomplished by either (non-)pharmacological rate or rhythm control in combination with optimal therapy of underlying cardiovascular morbidities and risk factors. Atrial fibrillation ablation has been performed in patients without overt heart failure successfully for many years. However, in recent years, attempts have been made for patients with heart failure as well. In this review, we discuss the current literature describing the treatment of atrial fibrillation in heart failure. We highlight the early rate versus rhythm control studies, the importance of addressing underlying conditions and treatment of risk factors. A critical evaluation will be performed of the catheter ablation studies that have been performed so far in light of larger (post-hoc) ablation studies. Furthermore, we will hypothesise the role of patient selection as next step in optimising outcome for patient with atrial fibrillation and heart failure.
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