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Study the interaction between juglone and calf thymus DNA by spectroscopic and molecular docking techniques

Bingjun Shen1, Huiru Yang1, Jiaqi Chen1

  • 1Department of Bioengineering, School of Life Science and Technology, Changchun University of Science and Technology, NO.7186 Weixing Road, Changchun City, Jilin Province 085238, PR China.

Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
|June 6, 2021
PubMed
Summary

Juglone, a compound from Cortex Juglandis Mandshuricae, interacts with calf thymus DNA (ctDNA). This study reveals Juglone intercalates into DNA, suggesting potential anti-cancer mechanisms.

Keywords:
Binding modeCalf thymus DNAInteractionJugloneMolecular docking technologySpectroscopy

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