Complementary use of priors for pulmonary imaging with electrical impedance and ultrasound computed tomography

For medical professionals caring for patients undergoing mechanical ventilation due to respiratory failure, the ability to quickly and safely obtain images of pulmonary function at the patient's bedside would be highly desirable. Such images could be used to provide early warnings of developing pulmonary pathologies in real time, thereby reducing the incidence of complications and improving patient outcomes. Electrical impedance tomography (EIT) and low-frequency ultrasound computed tomography (USCT) are two imaging techniques with the potential to provide real-time non-ionizing pulmonary monitoring in the ICU setting, and each method has its own unique advantages as well as drawbacks. In this work, we describe a new algorithm for a system in which the strengths of the two modalities are combined in a complementary fashion. Specifically, preliminary reconstructions from each modality are used as priors to stabilize subsequent reconstructions, providing improved spatial resolution, sharper organ boundaries, and enhanced appearance of pathologies and other features. Results are validated using three numerically simulated thoracic phantoms representing pulmonary pathologies.