Influence of transportation network on transmission heterogeneity of COVID-19 in China

In this paper, we propose a novel approach to model spatial heterogeneity for epidemic spreading, which combines the relevance of transport proximity in human movement and the excellent estimation accuracy of deep neural network. We apply this model to investigate the effects of various transportation networks on the heterogeneous propagation of COVID-19 in China. We further apply it to predict the development of COVID-19 in China in two scenarios, i.e., i) assuming that different types of traffic restriction policies are conducted and ii) assuming that the epicenter of the COVID-19 outbreak is in Beijing, so as to illustrate the potential usage of the model in generating various policy insights to help the containment of the further spread of COVID-19. We find that the most effective way to prevent the coronavirus from spreading quickly and extensively is to control the routes linked to the epicenter at the beginning of the pandemic. But if the virus has been widely spread, setting restrictions on hub cities would be much more efficient than imposing the same travel ban across the whole country. We also show that a comprehensive consideration of the epicenter location is necessary for disease control.