Ultra-minimum contrast percutaneous coronary intervention for a patient with complex coronary artery disease and
Keita Shibata1, Kohei Wakabayashi1, Ryota Kosaki1
1Division of Cardiology, Cardiovascular Center, Showa University Koto-Toyosu Hospital, 5-1-38, Toyosu, Koto-ku, Tokyo, Japan.
Insights
An invasive strategy did not improve outcomes for ischemic heart disease and advanced chronic kidney disease (CKD). However, minimal contrast percutaneous coronary intervention (PCI) improved renal function in a patient with end-stage CKD, avoiding dialysis.
Area of Science:
- Cardiology
- Nephrology
- Interventional Cardiology
Background:
- Patients with moderate to severe ischemic heart disease and advanced chronic kidney disease (CKD) often face poor prognoses.
- Contrast-induced nephropathy (CIN) is a known complication of percutaneous coronary intervention (PCI) that worsens outcomes.
- Minimizing contrast use during PCI may reduce CIN risk and improve clinical outcomes in this vulnerable population.
Observation:
- A 46-year-old woman with ischemic cardiomyopathy and end-stage diabetic nephropathy was scheduled for hemodialysis.
- She underwent PCI using an extremely low dose of contrast medium.
- Post-PCI, her renal function improved significantly, correlating with left ventricular function recovery.
Findings:
- The patient's improved renal function obviated the need for hemodialysis.
- She remained dialysis-free for over two years following coronary revascularization.
- This case demonstrates successful PCI with minimal contrast in a complex patient.
Implications:
- Aggressive examination and revascularization with minimal contrast are feasible and beneficial for severe heart failure patients with end-stage CKD.
- Specialized catheterization techniques are crucial for performing PCI with minimal contrast in high-risk patients.
- Coronary revascularization using minimal contrast may improve renal function in patients with end-stage CKD and severe ischemic cardiomyopathy.
Abstract:
A pivotal trial indicated that an initial invasive strategy did not improve the clinical outcomes in patients with moderate or severe ischemic heart disease and advanced chronic kidney disease (CKD) as compared with an initial conservative strategy. It is well known that contrast-induced nephropathy (CIN) is associated with worse prognosis after percutaneous coronary intervention (PCI). Minimum contrast PCI may lower the risk of CIN and improve the clinical outcomes of ischemic heart disease and advanced CKD. Here we report a case involving a 46-year-old woman with ischemic cardiomyopathy who was scheduled to start hemodialysis for end-stage diabetic nephropathy but exhibited improved renal function in accordance with the left ventricular function after PCI with an extremely low contrast dose. Accordingly, dialysis was not performed, and the patient did not require it for >2 years after coronary revascularization. The present case supports aggressive examination and revascularization for severe heart failure with an extremely low amount of contrast, even if the patient has complex coronary lesions and end-stage CKD. <Learning objective: It is important to treat with aggressive examination and revascularization for severe heart failure with an extremely low amount of contrast, even if the patient has end-stage chronic kidney disease (CKD). The technique of catheterization with minimum contrast is required for a special patient group. Coronary revascularization with an extremely small amount of contrast medium could improve renal function in patients with end-stage CKD and severely ischemic cardiomyopathy.>.
More Related Videos
10:28Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
07:25Predicting Amputation using Local Circulating Mononuclear Progenitor Cells in Angioplasty-treated Patients with Critical Limb Ischemia
Published on: September 22, 2020
Related Concept Videos
Cardiac Catheterization I: Pre-Procedure Overview
Peripheral Artery Disease III: Interprofessional Care
Imaging Studies for Cardiovascular System V: CT
Coronary Artery Disease V: Interprofessional Care
Acute Coronary Syndrome IV: Interprofessional Care
Acute Coronary Syndrome III: Diagnostic Studies
