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Aneurysmal and obstructive lesions of the left ventricular outflow: evaluation on multidetector computed tomography
Mumun Sinha1, Niraj N Pandey1, Arun Sharma1
1All India Institute of Medical Sciences, New Delhi, India.
Insights
The left ventricular outflow tract is complex and prone to various diseases. Multidetector computed tomography angiography aids in evaluating these structural abnormalities.
Area of Science:
- Cardiovascular Imaging
- Anatomical Pathology
Background:
- The left ventricular outflow tract (LVOT) is a critical cardiac region connecting the left ventricle to the aorta.
- It plays a vital role in valvular support and houses conduction system components.
- The LVOT is susceptible to diverse pathologies due to high pressure dynamics.
Purpose of the Study:
- To review the relevant anatomy of the left ventricular outflow tract.
- To describe the spectrum of structural abnormalities affecting the LVOT.
- To highlight the utility of multidetector computed tomography angiography (MDCT) in LVOT assessment.
Main Methods:
- Review of anatomical and pathological literature concerning the LVOT.
- Analysis of MDCT angiography findings in various LVOT abnormalities.
- Synthesis of imaging characteristics for diagnosis and management.
Main Results:
- Detailed anatomical description of the LVOT, including its relationship with the mitral valve and interventricular septum.
- Categorization of LVOT diseases as intraluminal, mural, or extramural.
- Demonstration of MDCT's capability in characterizing LVOT lesions and their local extension.
Conclusions:
- Comprehensive multimodality imaging is essential for evaluating LVOT diseases.
- MDCT angiography provides valuable insights into LVOT anatomy and pathology.
- Accurate assessment guides therapeutic decisions and follow-up strategies for LVOT conditions.
Abstract:
The left ventricular outflow is an anatomically complex region situated between the anterior leaflet of the mitral valve and the left ventricular aspect of the muscular and membranous interventricular septum. It gives rise to the aorta, provides support to the aortic valvular cusps, and houses important components of the conduction system. The left ventricular outflow handles high pressures and pressure variations and is subsequently affected by a variety of aetio-pathological conditions. Diseases involving the left ventricular outflow can be intraluminal, mural, or extramural, and the consequent complications of the lesions can be local, loco-regional, or even systemic. Appropriate evaluation requires comprehensive multimodality imaging with each modality contributing to assessment of different aspects of diagnosis, lesion characterization, local extension, prognostication for systemic complications and mortality, and the decision for the approach and type of intervention and aggressive follow-up in case non-interventional management is decided. In this review, we briefly describe the relevant anatomy and the gamut of structural abnormalities pertaining to the left ventricular outflow on multidetector computed tomography angiography.
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