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Updated: Nov 2, 2025

Flow Cytometry to Estimate Leukemia Stem Cells in Primary Acute Myeloid Leukemia and in Patient-derived-xenografts, at Diagnosis and Follow Up
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Published on: March 26, 2018

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Acute Myeloid Leukemia Complicated by Hyperleukocytosis and Leukostasis in the Emergency Department

Ryan T Ngo1, Amanda L Webb McAdams1, Anthony Furiato1

  • 1Emergency Medicine, Brandon Regional Hospital, Brandon, USA.

Cureus
|June 7, 2021
PubMed

Acute myeloid leukemia (AML) and other hematologic malignancies can be complicated by hyperleukocytosis, which leads to an increased risk for other severe complications such as tumor lysis syndrome, disseminated intravascular coagulation (DIC), and leukostasis. In this report, we present a case of a 65-year-old female with newly diagnosed AML complicated by leukostasis. We briefly review the clinical significance as well as initial diagnostic and therapeutic considerations pertaining to hyperleukocytosis and its associated complications.

Keywords:
acute myeloid leukemiablast crisishematologic malignancieshyperleukocytosisleukostasis

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