Related Experiment Video
Updated: Nov 2, 2025

Author Spotlight: A Focus on Standardized Salivary Gland Ultrasound Protocol in Connective Tissue Disease Research
Published on: October 13, 2023
Atypical Presentation of Salzmann Nodule: A Case Report and Literature Review
Mohanna Y Aljindan1, Malak A Bamashmoos2, Reem A AlShamlan3
1Ophthalmology, King Fahd University Hospital, Imam Abdulrahman Bin Faisal University, Dammam, SAU.
Abstract:
Salzmann's nodular degeneration (SND) is an unusual corneal condition that is slowly progressive and non-inflammatory in nature. It results in millimetric gray-white to bluish nodules formation anterior to Bowman's layer of the cornea. It usually affects both eyes in 80% of the cases. These elevated nodules are located near the limbus or in the mid-peripheral cornea, with some exceptions. Salzmann nodule develops following corneal trauma or inflammation. However, it can present idiopathically. Here, we report an atypical case of idiopathic symptomatic large central SND that was treated successfully with superficial keratectomy.

