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Prophylactic Erythropoietin for Neuroprotection in Very Preterm Infants: A Meta-Analysis Update
Hendrik S Fischer1, Nora J Reibel1, Christoph Bührer1
1Department of Neonatology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Frontiers in Pediatrics
|June 7, 2021
Abstract:
A meta-analysis update of randomized controlled trials investigating recombinant human erythropoietin suggests improved neurodevelopmental outcome in preterm infants. There was substantial heterogeneity, which could be ascribed to a single trial. Exclusion of this trial featuring a high risk of bias abolished heterogeneity and any effects of recombinant human erythropoietin treatment.

