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Utility of Non-invasive Cardiac Imaging Assessment in Coronavirus Disease 2019
Sandeep S Hothi1,2, Jin Jiang1, Richard P Steeds2,3
1Heart and Lung Centre, New Cross Hospital, Wolverhampton, United Kingdom.
Insights
Coronavirus disease 2019 (COVID-19) can cause cardiac complications, including acute myocardial injury. Non-invasive cardiac imaging helps assess the heart
Area of Science:
- Cardiology
- Infectious Diseases
- Medical Imaging
Background:
- Coronavirus disease 2019 (COVID-19) initially presented as a respiratory illness but cardiac complications are now recognized.
- Elevated high-sensitivity cardiac troponin (hs-cTn) indicates acute myocardial injury in COVID-19 patients, correlating with poor prognosis.
- Approximately 20-25% of patients with acute myocardial injury exhibit heart failure symptoms and increased mortality.
Purpose of the Study:
- To review the role of non-invasive cardiac imaging in evaluating cardiac involvement in COVID-19.
- To differentiate between direct and indirect cardiac effects of COVID-19 using imaging modalities.
- To explore the diagnostic and prognostic utility of cardiac imaging beyond serological biomarkers.
Main Methods:
- Review of current literature on non-invasive cardiac imaging techniques in COVID-19.
- Focus on established roles of echocardiography, cardiac MRI, and CT in cardiac assessment.
- Analysis of how imaging complements biomarker data for comprehensive cardiac evaluation.
Main Results:
- Non-invasive cardiac imaging provides crucial insights into cardiac structure and function in COVID-19.
- Imaging can distinguish between various causes of cardiac dysfunction related to the virus.
- Cardiac imaging offers prognostic information that supplements elevated hs-cTn levels.
Conclusions:
- Non-invasive cardiac imaging is essential for a thorough assessment of cardiac involvement in COVID-19.
- Imaging modalities enhance diagnostic accuracy and prognostic stratification in affected patients.
- Integrating imaging findings with biomarker data offers a more complete understanding of COVID-19's cardiac impact.
Abstract:
Coronavirus disease 2019 (COVID-19) was initially regarded as a disease of the lungs, which manifests as an acute respiratory illness and pneumonia, although more recently cardiac complications have been well-characterised. Serological cardiac biomarkers have been used to define acute myocardial injury, with significant elevation of high-sensitivity cardiac troponin (hs-cTn) associated with poor prognosis. Accordingly, 20-25% patients with acute myocardial injury (as defined by an elevated hs-cTn greater than the 99th percentile) have clinical signs of heart failure and increased mortality. An important outstanding clinical question is how best to determine the extent and nature of cardiac involvement in COVID-19. Non-invasive cardiac imaging has a well-established role in assessing cardiac structure and function in a wide range of cardiac diseases. It offers the potential to differentiate between direct and indirect COVID-19 effects upon the heart, providing incremental diagnostic and prognostic utility beyond the information yielded by elevated cardiac biomarkers in isolation. This review will focus on the non-invasive imaging assessment of cardiac involvement in COVID-19.
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