Risk Factors for Gastric Cancer-Associated Thrombotic Diseases in a Han Chinese Population

Area of Science:

• Oncology
• Hematology
• Epidemiology

Background:

• Gastric cancer (GC) is a significant global health concern.
• Thrombotic diseases are a serious complication in GC patients.
• Identifying risk factors for GC-associated thrombotic diseases is crucial for patient management.

Purpose of the Study:

• To investigate the independent risk factors for thrombotic diseases in a Han Chinese population with gastric cancer.
• To identify potential targets for early detection and preventive strategies in GC patients.

Main Methods:

• A case-control study involving 333 GC patients, with 68 in the case group (thrombotic diseases) and 265 in the control group.
• Data collection included general information, comorbidities, tumor characteristics, and treatment details.
• Univariate and multivariate logistic regression analyses were performed to identify significant risk factors.

Main Results:

• Age, diabetes, hypertension, histology, surgery, chemotherapy, and PICC use showed statistically significant differences between groups (P < 0.05).
• Independent risk factors for GC-associated thrombotic diseases were identified as age, diabetes, surgery, and PICC use (P < 0.05).

Conclusions:

• Thrombotic diseases in gastric cancer patients are significantly associated with age, diabetes, surgery, and PICC use.
• These findings suggest that age, diabetes, surgical intervention, and PICC placement are important considerations for preventing thrombophilia in GC patients.