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Updated: Nov 2, 2025

High-Resolution Three-Dimensional Imaging of the Footpad Vasculature in a Murine Hindlimb Gangrene Model

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Microvascular Hand Surgery for Digital Ischemia in Scleroderma.

Ellen S Satteson¹, Melody P Chung², Lorinda S Chung^2,3

¹Division of Plastic Surgery, Department of Surgery, The Robert A. Chase Hand Center, Stanford University Medical Center, Palo Alto, CA, USA.

Journal of Scleroderma and Related Disorders

|June 7, 2021

Summary

Microsurgical techniques like sympathectomy and bypass may improve digital pain and ulcers in systemic sclerosis (SSc) patients. Multidisciplinary care is key for managing SSc vascular issues in the hand.

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Area of Science:

Vascular Surgery
Rheumatology
Microsurgery

Background:

Systemic sclerosis (SSc) often causes digital pain and ulceration.
Medical management may be insufficient for persistent symptoms.
Microsurgical interventions are explored for vascular manifestations.

Purpose of the Study:

To review surgical techniques for SSc vascular hand issues.
To summarize outcomes and complications of periarterial sympathectomy and arterial bypass.
To highlight the role of multidisciplinary collaboration.

Main Methods:

Literature review of microsurgical techniques.
Analysis of relevant anatomy and medical therapies.
Evaluation of surgical outcomes and complications.

Main Results:

Periarterial sympathectomy and arterial bypass show potential for symptom improvement.
Surgical management addresses persistent digital pain and ulceration in SSc.
Multidisciplinary collaboration enhances patient management.

Conclusions:

Microsurgical options offer hope for SSc patients with severe vascular complications.
Optimal management requires integrated care from various specialties.
Further research into surgical outcomes is warranted.