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Joint hypermobility in primary mitral valve prolapse patients
1Research Institute of Rheumatic Disease, Piestány, Chechoslovakia.
Clinical Rheumatology
|March 1, 1988
Summary
Joint hypermobility is common in patients with mitral valve prolapse (MVP). This condition is linked to various joint issues and may involve increased antigen B 35 levels.
Area of Science:
- Cardiology
- Rheumatology
- Genetics
Background:
- Mitral valve prolapse (MVP) is a common cardiac condition.
- Joint hypermobility is a condition affecting connective tissues.
Purpose of the Study:
- To investigate the prevalence of joint hypermobility in patients with primary mitral valve prolapse.
- To explore potential associations between MVP, joint hypermobility, and arthrologic manifestations.
Main Methods:
- Twenty-seven patients with echocardiographic evidence of primary MVP were assessed.
- Joint hypermobility was evaluated using the Beighton and Horan criteria.
Main Results:
- Joint hypermobility was present in 52% of the MVP patients, a statistically significant finding.
- Patients with both MVP and joint hypermobility exhibited arthralgias, synovitic reactions, distortions, and low back pain.
- Increased functions of antigen B 35 were observed in patients with joint hypermobility.
Conclusions:
- There is a significant association between primary mitral valve prolapse and joint hypermobility.
- The co-occurrence of MVP and joint hypermobility may lead to various pathological arthrologic conditions.
- Antigen B 35 may play a role in patients with joint hypermobility.