Related Experiment Video
Updated: Nov 2, 2025

04:36
Noninvasive Electrocardiography in the Perinatal Mouse
Published on: June 12, 2020
6.3K
Computerized cardiotocography in singleton gestations with diabetes mellitus: a retrospective study
Elisabetta Gragnano1, Gabriele Saccone2, Salvatore Tagliaferri2
1Department of Neuroscience, Reproductive Sciences and Dentistry, School of Medicine, University of Naples Federico II, Naples, Italy - elisabettagragnano@gmail.com.
Minerva Obstetrics and Gynecology
|June 7, 2021
Summary
Computerized cardiotocography (C-CTG) monitoring revealed higher fetal heart rates in pregnant women with pre-pregnancy diabetes. Short-term variability (STV) and other parameters were lower in type 1 diabetes pregnancies compared to other groups.
Area of Science:
- Obstetrics and Gynecology
- Maternal-Fetal Medicine
- Diabetology
Background:
- Diabetes mellitus in pregnancy poses risks to fetal well-being.
- Accurate fetal monitoring is crucial for managing pregnancies complicated by diabetes.
Purpose of the Study:
- To evaluate the utility of computerized cardiotocography (C-CTG) for antenatal monitoring in women with diabetes mellitus.
- To compare C-CTG parameters across different diabetes types and a control group.
Main Methods:
- Retrospective cohort study of 298 pregnant women (January 2018 - January 2020).
- Included women with type 1 diabetes, type 2 diabetes, gestational diabetes mellitus (GDM), and a control group.
- Analyzed C-CTG data, focusing on short-term variability (STV), APRS, and DPRS.
Main Results:
- Fetal heart rate was significantly higher in women with pre-pregnancy diabetes (Type 1 and Type 2) versus GDM and controls.
- STV, APRS, and DPRS were significantly lower in women with Type 1 diabetes compared to Type 2, GDM, and control groups.
Conclusions:
- Pre-pregnancy diabetes (Type 1 and Type 2) is associated with elevated fetal heart rates.
- Reduced STV, APRS, and DPRS in Type 1 diabetes pregnancies suggest potential differences in fetal response to maternal diabetes.
Related Concept Videos
Diabetes Mellitus: Type 2 and Gestational
3.6K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
3.6K
Pathophysiology of Diabetes
2.2K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
2.2K

