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Related Concept Videos

CRISPR/Cas9 Genome Editing01:28

CRISPR/Cas9 Genome Editing

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The CRISPR-Cas system serves as a bacterial defense mechanism against invading genetic elements such as viruses and plasmids, forming the foundation for its adaptation as a powerful genome-editing tool. Originally discovered in prokaryotes, this system has been repurposed to revolutionize genetic engineering across a wide range of organisms, including plants, animals, and humans. The core component, Cas9, is an endonuclease derived from Streptococcus pyogenes, capable of introducing...
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Genome editing technologies allow scientists to modify an organism’s DNA via the addition, removal, or rearrangement of genetic material at specific genomic locations. These types of techniques could potentially be used to cure genetic disorders such as hemophilia and sickle cell anemia. One popular and widely used DNA-editing research tool that could lead to safe and effective cures for genetic disorders is the CRISPR-Cas9 system. CRISPR-Cas9 stands for Clustered Regularly Interspaced...
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Bacteria and archaea are susceptible to viral infections just like eukaryotes; therefore, they have developed a unique adaptive immune system to protect themselves. Clustered regularly interspaced short palindromic repeats and CRISPR-associated proteins (CRISPR-Cas) are present in more than 45% of known bacteria and 90% of known archaea.
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Homologous Recombination02:31

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The basic reaction of homologous recombination (HR) involves two chromatids that contain DNA sequences sharing a significant stretch of identity. One of these sequences uses a strand from another as a template to synthesize DNA in an enzyme-catalyzed reaction. The final product is a novel amalgamation of the two substrates. To ensure an accurate recombination of sequences, HR is restricted to the S and G2 phases of the cell cycle. At these stages, the DNA has been replicated already and the...
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Plant Breeding and Biotechnology01:59

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Crop cultivation has a long history in human civilization, with records showing the cultivation of cereal plants beginning at around 8000 BC. This early plant breeding was developed primarily to provide a steady supply of food.
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Updated: Nov 2, 2025

Author Spotlight: Streamlining Rice Breeding with CRISPR/Cas for Obtaining Optimal Phenotypic and Agronomic Traits
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CRISPR Genome Editing Technology: A Powerful Tool Applied to Developing Agribusiness.

Mariana Rocha Maximiano1,2, Fabiano T P K Távora3,4, Guilherme Souza Prado5

  • 1S-Inova Biotech, Pós-Graduação em Biotecnologia, Universidade Católica Dom Bosco, Campo Grande, Mato Grosso do Sul 79117-900, Brazil.

Journal of Agricultural and Food Chemistry
|June 7, 2021
PubMed
Summary

Gene editing with CRISPR/Cas technology offers a powerful solution to enhance agricultural productivity and ensure global food security amidst population growth and climate change challenges. This biotechnology revolutionizes agribusiness by improving crops and livestock for better yields and quality.

Keywords:
CRISPR/Cas systemagricultural commoditiesaquaculturefarm animalsfood-trait improvementgenome editingplant crops

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Area of Science:

  • Agricultural Science
  • Biotechnology
  • Genetics

Background:

  • Global population increase necessitates higher agricultural output.
  • Climate change poses significant challenges to food security.
  • CRISPR/Cas gene editing offers precise genomic manipulation capabilities.

Purpose of the Study:

  • To review the CRISPR/Cas system's role in advancing agribusiness.
  • To highlight its applications in improving key agricultural traits.
  • To discuss its impact on food security, socioeconomics, and human health.

Main Methods:

  • Review of current research on CRISPR/Cas applications in agriculture.
  • Analysis of studies demonstrating trait enhancement in plants and animals.
  • Synthesis of findings on economic and health impacts.

Main Results:

  • CRISPR/Cas successfully enhances desirable traits in major crops and farm animals.
  • Demonstrated improvements in crop yield, seed quality, animal productivity, and welfare.
  • Positive socioeconomic and human health implications observed.

Conclusions:

  • CRISPR/Cas system is a revolutionary tool for agricultural biotechnology.
  • Its application in agribusiness is poised to significantly improve food production and security.
  • The technology holds immense potential for sustainable agriculture and global well-being.