Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

13.0K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
13.0K
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic01:26

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic

5.0K
Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
5.0K
Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

3.3K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
3.3K
Tonsillitis I: Introduction01:30

Tonsillitis I: Introduction

819
Tonsillitis is inflammation of the tonsils, which are two lymphoid tissue masses at the back of the throat. This condition can cause discomfort and irritation in the throat.
Etiology
Three primary contributing factors have been identified.
819
Endocarditis I: Introduction01:25

Endocarditis I: Introduction

111
Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
111
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

72
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
72

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

CAR T Cell Therapy as a Definitive Consolidation for Older Adults with B-ALL in First Complete Remission.

Blood advances·2026
Same author

Beyond the Tip of the Iceberg: The Clinical Impact of Maternal Nonprimary Cytomegalovirus Infection.

The Pediatric infectious disease journal·2026
Same author

Fit cells, fertile ground: Immunometabolic programming and bone marrow niche support in durable CAR T cell response in leukemia.

Molecular therapy. Oncology·2026
Same author

PET/CT as a Diagnostic Tool in Pediatric Fever of Unknown Origin: A Multicenter Study.

Pediatrics·2026
Same author

Fast Antimicrobial Susceptibility Testing for Gram-Negative Bacteremia: The FAST Randomized Clinical Trial.

JAMA·2026
Same author

The role of ultrasound in decision-making for the management of suspected acute appendicitis during pregnancy.

European journal of obstetrics, gynecology, and reproductive biology·2026

Related Experiment Video

Updated: Nov 2, 2025

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA
12:18

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA

Published on: February 9, 2011

23.2K

Invasive Group A Streptococcus Infection in Children in Central Israel in 2012-2019.

Michal Canetti1, Amit Carmi2, Gideon Paret1,2

  • 1From the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

The Pediatric Infectious Disease Journal
|June 7, 2021
PubMed
Summary
This summary is machine-generated.

Invasive group A Streptococcus infections (iGASi) in children increased by 37% between 2012-2019. This rise highlights the need for enhanced surveillance and research into pediatric iGASi.

More Related Videos

A Murine Model of Group B Streptococcus Vaginal Colonization
10:19

A Murine Model of Group B Streptococcus Vaginal Colonization

Published on: November 16, 2016

14.7K
Implementation of a Permeable Membrane Insert-based Infection System to Study the Effects of Secreted Bacterial Toxins on Mammalian Host Cells
09:25

Implementation of a Permeable Membrane Insert-based Infection System to Study the Effects of Secreted Bacterial Toxins on Mammalian Host Cells

Published on: August 19, 2016

11.2K

Related Experiment Videos

Last Updated: Nov 2, 2025

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA
12:18

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA

Published on: February 9, 2011

23.2K
A Murine Model of Group B Streptococcus Vaginal Colonization
10:19

A Murine Model of Group B Streptococcus Vaginal Colonization

Published on: November 16, 2016

14.7K
Implementation of a Permeable Membrane Insert-based Infection System to Study the Effects of Secreted Bacterial Toxins on Mammalian Host Cells
09:25

Implementation of a Permeable Membrane Insert-based Infection System to Study the Effects of Secreted Bacterial Toxins on Mammalian Host Cells

Published on: August 19, 2016

11.2K

Area of Science:

  • Pediatric Infectious Diseases
  • Epidemiology
  • Microbiology

Background:

  • Group A Streptococcus (GAS) causes serious pediatric diseases.
  • Recent years show an unexplained rise in invasive group A Streptococcus infections (iGASi).
  • Understanding iGASi epidemiology in children is crucial.

Purpose of the Study:

  • To describe the epidemiology of iGASi in hospitalized children in central Israel.
  • To detail clinical and demographic characteristics of pediatric iGASi.
  • To analyze outcomes of iGASi in pediatric patients.

Main Methods:

  • Retrospective analysis of medical records for children (<18 years) diagnosed with iGASi (2012-2019).
  • Data collection included clinical, laboratory, microbiologic, and immunization status.
  • Patients were stratified into severe and non-severe groups; emm type was determined.

Main Results:

  • 167 patients with 206 positive GAS cultures identified.
  • Hospitalizations for iGASi increased by 37% (701 to 958 per 100,000 admissions) between 2012-2015 and 2016-2019.
  • Common sites included otolaryngologic, blood, soft tissue, and respiratory; mastoiditis and bacteremia were frequent diagnoses, with pneumonia prevalent in severe cases.

Conclusions:

  • Pediatric iGASi admissions have risen over the past eight years.
  • Enhanced surveillance and prospective studies are needed to understand iGASi epidemiology and pathogenesis in children.
  • Monitoring emm-type distribution is essential for tracking iGASi trends.