Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Slow transit constipation. Comparison between patients with or without previous hysterectomy.

A M Roe1, D C Bartolo, N J Mortensen

  • 1University Department of Surgery, Bristol Royal Infirmary, U.K.

Digestive Diseases and Sciences
|September 1, 1988
PubMed
Summary

This study compared slow transit constipation (STC) in patients post-hysterectomy versus those with de novo STC. De novo STC showed clear abnormalities, while hysterectomy

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Development and early outcomes of the national training initiative for transanal total mesorectal excision in the UK.

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland·2020
Same author

Short- and long-term outcomes of strictureplasty for obstructive Crohn's disease.

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland·2020
Same author

Multicentre phase II trial of near-infrared imaging in elective colorectal surgery.

The British journal of surgery·2018
Same author

Subtotal colectomy for ulcerative colitis: lessons learned from a tertiary centre.

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland·2017
Same author

The treatment of all MRI-defined low rectal cancers in a single expert centre over a 5-year period: is there room for improvement?

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland·2016
Same author

A two-centre experience of transanal total mesorectal excision.

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland·2016

Area of Science:

  • Gastroenterology
  • Colorectal Surgery
  • Pelvic Health

Background:

  • Slow transit constipation (STC) is a debilitating condition affecting bowel motility.
  • The potential link between hysterectomy and the development of STC requires further investigation.
  • Understanding specific physiological abnormalities can differentiate STC etiologies.

Purpose of the Study:

  • To investigate potential differences in anorectal function between patients with de novo STC and those with STC following hysterectomy.
  • To identify specific physiological markers associated with STC in relation to pelvic surgery.

Main Methods:

  • Comparative study of 31 patients with STC, divided into de novo (n=17) and post-hysterectomy (n=14) groups.
  • Assessment of rectosigmoid motility, anal canal pressures, rectoanal inhibitory reflex, anorectal angle during straining, rectal sensory thresholds, and external sphincter electromyography.

Related Experiment Videos

  • Comparison with healthy controls for rectal sensory thresholds.

    • Main Results:

    • The de novo STC group exhibited impaired rectosigmoid motility and a higher sensory threshold for rectal filling compared to controls.
    • External sphincter electromyography revealed inappropriate inhibition of resting activity in 57% of the de novo group and 38% of the post-hysterectomy group.
    • Abnormalities in the post-hysterectomy group were less distinct, with no significant difference in sensory thresholds compared to controls.

    Conclusions:

    • De novo STC is characterized by rectosigmoid hypoactivity and rectal hyposensitivity.
    • The physiological basis for STC developing after hysterectomy remains unclear.
    • A definitive link between hysterectomy and specific STC abnormalities is not established by this study.