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Updated: Nov 2, 2025

Sequencing of mRNA from Whole Blood using Nanopore Sequencing
Published on: June 3, 2019
The emerging landscape of single-molecule protein sequencing technologies
Javier Antonio Alfaro1, Peggy Bohländer2, Mingjie Dai3,4
1International Centre for Cancer Vaccine Science, University of Gdańsk, Gdańsk, Poland. javier.alfaro@proteogenomics.ca.
Abstract:
Single-cell profiling methods have had a profound impact on the understanding of cellular heterogeneity. While genomes and transcriptomes can be explored at the single-cell level, single-cell profiling of proteomes is not yet established. Here we describe new single-molecule protein sequencing and identification technologies alongside innovations in mass spectrometry that will eventually enable broad sequence coverage in single-cell profiling. These technologies will in turn facilitate biological discovery and open new avenues for ultrasensitive disease diagnostics.
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