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A country-specific FRAX model for Botswana.
M Kebaetse1, S Nkhwa1, M Mogodi1
1Faculty of Medicine, University of Botswana, Gaborone, Botswana.
Archives of Osteoporosis
|June 8, 2021
Summary
A new FRAX® model for Botswana was developed to assess fracture risk. This tool is expected to aid in preventing and treating fragility fractures across the nation.
Area of Science:
- Public Health
- Epidemiology
- Orthopedics
Background:
- Osteoporotic fractures pose a significant health burden globally.
- Country-specific fracture risk assessment tools are crucial for targeted interventions.
- Botswana previously lacked a localized FRAX® model for fracture risk assessment.
Purpose of the Study:
- To develop and characterize a country-specific FRAX® model for Botswana.
- To enable accurate fracture risk assessment for the Botswana population.
- To inform public health strategies for osteoporosis management in Botswana.
Main Methods:
- Incorporated age-specific and sex-specific hip fracture incidence data for Botswana.
- Utilized national mortality rates in the FRAX® model development.
- Compared 10-year fracture probabilities with existing FRAX® models from other African nations and US populations.
Main Results:
- Developed a FRAX® model tailored to Botswana's demographic and epidemiological profile.
- Fracture probabilities in Botswana were found to be lower than in South Africa (Black and Coloured) and US Blacks.
- Probabilities were marginally higher compared to Tunisia, indicating a unique risk profile.
Conclusions:
- The newly developed FRAX® model for Botswana provides a vital tool for fracture risk assessment.
- This model is anticipated to significantly guide clinical decisions regarding the prevention and treatment of fragility fractures in Botswana.
- Facilitates evidence-based strategies for managing osteoporosis and reducing fracture incidence.
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