Cost factors in limb-threatening ischaemia due to infrainguinal arteriosclerosis

S K Gupta1, F J Veith, E Ascer

  • 1Department of Surgery, Montefiore Medical Center/Albert Einstein College of Medicine, New York, NY 10467.

Insights

Infrainguinal atherosclerosis treatment via vascular reconstruction or amputation is costly. Limb salvage rates were high, but associated costs were significant, especially with risk factors like gangrene or advanced age.

Area of Science:

  • Vascular Surgery
  • Health Economics
  • Atherosclerosis Research

Background:

  • Limb-threatening ischemia due to infrainguinal atherosclerosis affects over 150,000 US patients annually.
  • Cost is a critical factor in managing medical conditions, including peripheral arterial disease.
  • Understanding the economic impact of treatment options is vital for patient care and resource allocation.

Purpose of the Study:

  • To evaluate the economic impact of treating limb-threatening ischemia caused by infrainguinal atherosclerosis.
  • To compare the costs and outcomes of vascular reconstruction versus primary below-knee amputation.
  • To identify cost-associated risk factors in patients with severe peripheral arterial disease.

Main Methods:

  • Retrospective study of 313 consecutive patients treated between 1979-1981.
  • Minimum 3-year follow-up to assess limb salvage and functional outcomes.
  • Analysis of patient costs, length of stay, and risk factor impact on expenditure.

Main Results:

  • Vascular reconstruction achieved limb salvage with full function in 79% at 1 year and 60% at 3 years.
  • Mean cost for arterial reconstructions was $26,194; mean length of stay was 50 days.
  • Risk factors like gangrene, age >70, and prior surgery significantly increased costs; below-knee amputation had high long-term costs for nonambulatory patients.

Conclusions:

  • Both vascular reconstruction and primary amputation for infrainguinal atherosclerosis are associated with substantial costs.
  • Vascular reconstruction offers high limb salvage rates, but carries significant financial implications.
  • Adverse risk factors increase treatment costs, highlighting the need for cost-effective management strategies.

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