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Updated: Nov 2, 2025

A Model for Epilepsy of Infectious Etiology using Theiler's Murine Encephalomyelitis Virus
Published on: June 23, 2022
Infectious causes of Alice in Wonderland syndrome
Luis Perez-Garcia1,2,3, Oriana Pacheco1,2,3, Lourdes Delgado-Noguera1,2,3
1Infectious Diseases Division, Venezuelan Science Incubator and the Zoonosis and Emerging Pathogens Regional Collaborative Network, Barquisimeto, Lara, Venezuela.
Abstract:
Alice-in-Wonderland syndrome (AIWS) is a perceptual disorder embracing a spectrum of self-experienced paroxysmal body image illusions including most commonly distortions of shape (metamorphopsia), size (macropsia or micropsia), distance (pelopsia or teleopsia), movement, and color among other visual and somesthetic distortions. Depersonalization, derealization, and auditory hallucinations have also been described. Recent reports suggest that infectious diseases are the predominant etiology for AIWS, especially among children. This article reviews current understanding regarding the association between infection and development of AIWS.
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