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Published on: October 21, 2022
Evaluation of the corneal endothelium by specular microscopy in patients with chronic obstructive pulmonary disease
Murat Serkan Songur1, Yavuz Selim İntepe2, Seray Aslan Bayhan1
1Faculty of Medicine, Department of Ophthalmology, Yozgat Bozok University, Yozgat, Turkey.
Objective:
The objective of this study is to evaluate the corneal endothelium in patients with chronic obstructive pulmonary disease (COPD) using a specular microscope.
Methods:
The right eyes of 64 patients with a COPD diagnosis and 65 healthy individuals were evaluated. Cell density (CD) (cell/mm2 ), corneal thickness (CT) (μ), hexagonal cell ratio (%), and coefficient of variation (cell area standard deviation/mean cell area, μm2 ) were analyzed by specular microscopy (SM).
Results:
The CT was significantly reduced in the COPD group compared with the control group (P = 0.021). Moreover, a significant difference was found between the COPD group and the control group in terms of corneal endothelial CD (P = 0.011), hexagonal cell ratio (P = 0.008), and coefficient of variation (P = 0.012).
Conclusion:
The corneal endothelial structure was significantly deteriorated in patients with COPD compared with the control group. SM is a valuable method that could be used in treatment and follow-up of corneal endothelium in patients with COPD.
