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Dual attention multiple instance learning with unsupervised complementary loss for COVID-19 screening.

Philip Chikontwe1, Miguel Luna1, Myeongkyun Kang1

  • 1Department of Robotics Engineering, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu, South Korea.

Medical Image Analysis
|June 8, 2021
PubMed
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This summary is machine-generated.

This study introduces a novel AI framework for diagnosing COVID-19 and bacterial pneumonia using chest CT scans. The Dual Attention Contrastive based Multiple Instance Learning (DA-CMIL) model achieves high accuracy, aiding rapid and reliable disease detection.

Area of Science:

  • Medical Imaging
  • Artificial Intelligence
  • Infectious Disease Diagnostics

Background:

  • Chest computed tomography (CT) is crucial for diagnosing Coronavirus Disease 2019 (COVID-19), especially given limitations of RT-PCR.
  • Accurate CT-based diagnosis is challenging due to annotation difficulties and similarities between COVID-19 and other pneumonias.

Purpose of the Study:

  • To develop an advanced, weakly supervised framework for rapid COVID-19 and bacterial pneumonia diagnosis using chest CT.
  • To enhance diagnostic accuracy through attention mechanisms and contrastive learning.

Main Methods:

  • Proposed Dual Attention Contrastive based Multiple Instance Learning (DA-CMIL) framework.
  • Utilized attention mechanisms for spatial and latent context, combined with unsupervised contrastive learning.
Keywords:
COVID-19CT imagesDeep learningMultiple instance learningUnsupervised complementary loss

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  • Trained on multiple patient CT slices (instances) to output a single diagnostic label.
  • Main Results:

    • Achieved an overall accuracy of 98.6% and an Area Under the Curve (AUC) of 98.4%.
    • Demonstrated the effectiveness of contrastive learning integrated with Multiple Instance Learning (MIL).
    • Spatial attention provided interpretable diagnostic insights.

    Conclusions:

    • The DA-CMIL framework offers a highly accurate and efficient method for diagnosing COVID-19 and bacterial pneumonia from chest CT scans.
    • Attention and contrastive learning significantly improve diagnostic performance in weakly supervised settings.