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Updated: Nov 2, 2025

Inducement and Evaluation of a Murine Model of Experimental Myopia
Published on: January 22, 2019
Topiramate-induced Acute Transient Myopia and Angle Narrowing
Summaya Khan1, Ammarah Ashraf1, Hassaan Javaid1
1Armed Forces Institute of Ophthalmology, Rawalpindi, Pakistan.
Abstract:
Sulphamate drugs, widely prescribed for various systemic conditions, are reported to have rare ocular adverse-effects, usually within weeks of initiation of treatment. Medical and drug history in such cases are of pivotal importance in reaching a proper diagnosis. This study reports three cases, which developed topiramate-induced ocular side effects. In one of the cases, although the angles were narrow in both eyes, yet intra-ocular pressure (IOP) was not high. Also, in the third case, there were no macular striae. Topiramate was immediately withheld and all cases were improved without any permanent ocular damage. Key Words: Sulphamate, Topiramate, Angle closure glaucoma, Myopia.
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