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Lacosamide-induced sinus node dysfunction followed by severe agranulocytosis.

Makoto Shibata1, Reona Hoshino1, Chisato Shimizu1

  • 1Department of Neurology, Takasaki General Medical Center, National Hospital Organization, 36 Takamatsu-cho, Takasaki, 370-0829, Gunma, Japan.

BMC Neurology
|June 9, 2021
PubMed
Summary

Lacosamide (LCM), an antiepileptic drug, can cause severe sinus node dysfunction (SND) and agranulocytosis. This case highlights the risk of simultaneous adverse events during early LCM treatment, necessitating careful patient monitoring.

Keywords:
Adverse effectsAgranulocytosisLacosamideNeutropeniaSinus node dysfunction

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