Related Experiment Video

Updated: Nov 2, 2025

A Magnetic Resonance Imaging-based Computational Protocol for Analysis of Plaque Morphology and Hemodynamics in Patients with Carotid Artery Stenosis
09:36

A Magnetic Resonance Imaging-based Computational Protocol for Analysis of Plaque Morphology and Hemodynamics in Patients with Carotid Artery Stenosis

Published on: August 12, 2025

231

Symptomatic internal carotid artery dissection and kinking in a patient with fibromuscular dysplasia

Victor Bilman1, Luca Apruzzi1, Domenico Baccellieri1

  • 1"Vita - Salute" University, Scientific Institute H. San Raffaele, Milan, Italy.

Jornal Vascular Brasileiro
|June 9, 2021
PubMed

Insights

Fibromuscular dysplasia (FMD) can cause internal carotid artery (ICA) dissection, especially with artery kinks. Surgical repair via bypass proved effective for a patient with FMD-related ICA dissection and stenosis.

Area of Science:

  • Vascular Surgery
  • Neurology
  • Pathology

Background:

  • Cervical artery dissection, particularly isolated internal carotid artery (ICA) dissection, is uncommon in younger individuals.
  • Fibromuscular dysplasia (FMD) is a strong etiological consideration in such cases, especially when accompanied by arterial elongation and tortuosity.
  • The natural history and optimal management strategies for cerebrovascular FMD remain incompletely understood, posing challenges for symptomatic patients.

Observation:

  • A 44-year-old female presented with a transient ischemic attack (TIA) without typical cardiovascular risk factors.
  • She exhibited an isolated left ICA dissection and significant kinking.
  • Carotid duplex ultrasound revealed severe left ICA stenosis secondary to the dissection.

Findings:

  • Histopathological examination confirmed FMD as the underlying cause of the dissection.
  • Surgical intervention involving an autogenous great saphenous vein bypass was performed.
  • The patient experienced an uneventful recovery following the surgical repair.

Implications:

  • Cervical carotid artery dissection may indicate an underlying arterial pathology like FMD.
  • The presence of ICA tortuosity introduces unique considerations for effective patient management.
  • Surgical intervention, such as bypass grafting, can be a viable and successful treatment option for FMD-related ICA dissection.
Keywords:
arterial dissectioncarotid arterycoilingfibromuscular dysplasiakinking

More Related Videos

A Rat Carotid Artery Pressure-Controlled Segmental Balloon Injury with Periadventitial Therapeutic Application06:53

A Rat Carotid Artery Pressure-Controlled Segmental Balloon Injury with Periadventitial Therapeutic Application

Published on: July 9, 2020

5.2K
A Model of Disturbed Flow-Induced Atherosclerosis in Mouse Carotid Artery by Partial Ligation and a Simple Method of RNA Isolation from Carotid Endothelium11:00

A Model of Disturbed Flow-Induced Atherosclerosis in Mouse Carotid Artery by Partial Ligation and a Simple Method of RNA Isolation from Carotid Endothelium

Published on: June 22, 2010

29.1K

Related Concept Videos

Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
64
Aneurysm I: Introduction01:30

Aneurysm I: Introduction

An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
92
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
109
Arteries of the Head and Neck01:26

Arteries of the Head and Neck

The human body's intricate network of arteries ensures that every organ system receives the necessary oxygen and nutrients for optimal function. The arterial network in the head and neck region is particularly complex, providing vital blood flow to the brain, eyes, and other critical structures. Prominent arteries in this region include the internal carotid arteries and the vertebral arteries.
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...
2.1K
The Arch of Aorta01:10

The Arch of Aorta

The coronary arteries, originating from the ascending aorta, bifurcate from two sinuses located within the ascending aorta. Positioned just above the aortic semilunar valve, these sinuses house essential aortic baroreceptors and chemoreceptors, crucial for maintaining cardiac function. The left coronary artery and the right coronary artery branch off from the left posterior and anterior aortic sinuses, respectively.
Encircling the heart, the coronary arteries form a ring-like structure before...
1.2K
Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
74