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Persistent Left Superior Vena Cava: Why is Prenatal Diagnosis Important?
Ayşe Keleş1, Osman Yılmaz2, Gülşah Dağdeviren1
1Perinatology Department, University of Health Sciences Etlik Zübeyde Hanım Women's Health Care, Training and Research Hospital, Ankara, Turkey.
Fetal and Pediatric Pathology
|June 9, 2021
Summary
Persistent left superior vena cava (PLSVC) in fetuses often accompanies other anomalies, necessitating careful examination and genetic counseling. Postnatal evaluation is crucial for detecting conditions like coarctation of the aorta.
Area of Science:
- Cardiology
- Prenatal Diagnosis
- Medical Genetics
Background:
- Persistent left superior vena cava (PLSVC) is a rare congenital anomaly.
- Understanding associated fetal anomalies and pregnancy outcomes is vital for prenatal care.
Purpose of the Study:
- To investigate fetal anomalies and pregnancy outcomes in pregnancies with PLSVC.
- To aid in prenatal counseling for PLSVC cases.
Main Methods:
- Retrospective analysis of 27 cases diagnosed with PLSVC between January 2015 and January 2020.
- Review of electronic medical records for fetal anatomy and pregnancy outcomes.
Main Results:
- PLSVC prevalence was 6.9% among congenital heart diseases (CHD).
- Conotruncal and renal anomalies were the most frequent cardiac and extracardiac findings, respectively.
- One fetus had a chromosomal abnormality; one postpartum case revealed coarctation of the aorta (CoA).
Conclusions:
- Prenatal ultrasonography detection of PLSVC requires thorough fetal anatomical examination.
- Genetic counseling is recommended for PLSVC cases with additional anomalies.
- Isolated PLSVC warrants repeated echocardiography to assess for CoA risk.
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