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A patient with methotrexate lung and granulomatous changes in the liver--or just sarcoidosis?
C T van Deursen1, J Koudstaal, F P Maesen
1Department of Respiratory Diseases, De Weverhospital, Heerlen, The Netherlands.
International Journal of Clinical Pharmacology, Therapy, and Toxicology
|June 1, 1988
Abstract:
A 57 year old ex-miner, who had been treated for his psoriasis with methotrexate 5 mg 3 times a week, taken orally (in total +/- 12 g) developed in the spring 1985 the symptoms of an allergic pneumonia. In biopsies of lung and liver non-caseating granulomata were found, compatible with the diagnosis sarcoidosis. The question whether one clinical entity is concerned or two superponed diseases, remains unanswered.