Related Experiment Videos
Uterine NK cell education: Learning the ropes in pregnancy
Alexandra I Wells1, Carolyn B Coyne1
1Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA.
Immunity
|June 9, 2021
Abstract:
The impact of inhibitory receptor NKG2A-mediated education on uterine NK (uNK) cell responsiveness to vascular remodeling on pregnancy outcomes has remained unclear. In this issue of Immunity, Shreeve et al. show that loss of NKG2A+ uNK cells results in deficient vascularization and restricted fetal growth.