Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Protein Networks02:26

Protein Networks

4.2K
An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
4.2K
Environmental Applications of Microorganisms01:30

Environmental Applications of Microorganisms

542
Microorganisms play a pivotal role in maintaining ecosystem balance by recycling essential elements such as carbon, nitrogen, and phosphorus, as well as supporting processes like bioremediation, wastewater treatment, and biofuel production.Microbes in Elemental CyclesIn the carbon cycle, microorganisms decompose organic matter, releasing carbon dioxide via aerobic respiration. This carbon dioxide is subsequently used by photosynthetic organisms to synthesize organic compounds, closing the...
542
Modern Molecular Taxonomy01:29

Modern Molecular Taxonomy

318
Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...
318

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Modelling the role of the microbiome in antimicrobial resistance across scales.

Nature microbiology·2026
Same author

PlasticEnz: An integrated database and screening tool combining homology and machine learning to identify plastic-degrading enzymes in meta-omics datasets.

PLoS computational biology·2026
Same author

Keystone concept revisited: insights into microbial community dynamics and control.

Nature reviews. Microbiology·2026
Same author

Emergence of alternative states in a synthetic human gut microbial community.

Nature communications·2025
Same author

Growth stage and interspecies interactions shape the cell biology and cell cycle characteristics of human gut bacteria Bacteroides thetaiotaomicron and Roseburia intestinalis.

Communications biology·2025
Same author

Differential recovery of chain-elongating bacteria: comparing droplet, plating, and dilution-to-extinction methods.

mSystems·2025
Same journal

Host life-history strategy is a critical determinant of virulent phage infection propensity.

The ISME journal·2026
Same journal

Trichoderma enriches Burkholderia via cross-feeding of degradation intermediates to enhance atrazine degradation and alleviate soybean phytotoxicity.

The ISME journal·2026
Same journal

Density-mediated freshwater plastisphere microbiomes preferentially degrade conventional rather than biodegradable microplastics.

The ISME journal·2026
Same journal

Metabolic interactions enable aerobic degradation of the environmental pollutant BDE-47.

The ISME journal·2026
Same journal

Cyanobacterial flocculation as a defence against bacterial predation.

The ISME journal·2026
Same journal

Acidifying bacteria inhibit pathogenic bacteria more strongly with increasing glucose.

The ISME journal·2026
See all related articles

Related Experiment Video

Updated: Nov 2, 2025

Assembly and Tracking of Microbial Community Development within a Microwell Array Platform
09:24

Assembly and Tracking of Microbial Community Development within a Microwell Array Platform

Published on: June 6, 2017

9.2K

Open challenges for microbial network construction and analysis.

Karoline Faust1

  • 1KU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Leuven, Belgium. karoline.faust@kuleuven.be.

The ISME Journal
|June 10, 2021
PubMed
Summary
This summary is machine-generated.

Microbial network construction is key in microbiome research. This perspective highlights overlooked challenges in building and interpreting these complex microbial networks.

More Related Videos

Mapping Bacterial Functional Networks and Pathways in Escherichia Coli using Synthetic Genetic Arrays
14:06

Mapping Bacterial Functional Networks and Pathways in Escherichia Coli using Synthetic Genetic Arrays

Published on: November 12, 2012

46.7K
Divergence of Root Microbiota in Different Habitats based on Weighted Correlation Networks
09:49

Divergence of Root Microbiota in Different Habitats based on Weighted Correlation Networks

Published on: September 25, 2021

4.5K

Related Experiment Videos

Last Updated: Nov 2, 2025

Assembly and Tracking of Microbial Community Development within a Microwell Array Platform
09:24

Assembly and Tracking of Microbial Community Development within a Microwell Array Platform

Published on: June 6, 2017

9.2K
Mapping Bacterial Functional Networks and Pathways in Escherichia Coli using Synthetic Genetic Arrays
14:06

Mapping Bacterial Functional Networks and Pathways in Escherichia Coli using Synthetic Genetic Arrays

Published on: November 12, 2012

46.7K
Divergence of Root Microbiota in Different Habitats based on Weighted Correlation Networks
09:49

Divergence of Root Microbiota in Different Habitats based on Weighted Correlation Networks

Published on: September 25, 2021

4.5K

Area of Science:

  • Microbiome research
  • Bioinformatics
  • Data analysis

Background:

  • Microbial network construction is a widely used technique for exploring relationships within microbial communities.
  • Numerous tools exist for microbial network construction, yet critical issues remain unaddressed.

Purpose of the Study:

  • To identify and discuss underexplored challenges in microbial network construction.
  • To encourage further research into the analysis and interpretation of microbial networks.

Main Methods:

  • Perspective piece
  • Literature review
  • Critical analysis of existing methodologies

Main Results:

  • Identified several key challenges in microbial network construction and interpretation.
  • Highlighted the need for standardized approaches and robust validation methods.

Conclusions:

  • Addressing these challenges is crucial for advancing microbiome research.
  • Further investigation is needed to improve the reliability and interpretability of microbial networks.