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Eye Tracking Young Children with Autism
Published on: March 27, 2012
Early concerns in parents of infants at risk for autism
Amanda T Tran1, Mithi Del Rosario1,2, Erin Nosco3
1David Geffen School of Medicine at the University of California, Los Angeles, CA, USA.
Insights
Parents of high-risk infants for autism spectrum disorder (ASD) began reporting concerns by 6 months. By 12 months, parents of atypically developing high-risk infants identified ASD-related concerns, aiding early detection.
Area of Science:
- Developmental Pediatrics
- Autism Spectrum Disorder Research
- Child Psychology
Background:
- Early identification of autism spectrum disorder (ASD) is crucial for timely intervention.
- Parental concerns are a key indicator in monitoring infant development, particularly in high-risk populations.
- Familial risk significantly influences the likelihood of developing ASD.
Purpose of the Study:
- To investigate parental concerns in infants with a high familial risk of ASD.
- To track the emergence and nature of ASD-related and general concerns over the first 18 months of life.
- To differentiate concerns based on infant outcome (typically developing vs. atypically developing) within the high-risk group.
Main Methods:
- Prospective collection of parental concerns (ASD-related and general) from 76 infants (high-risk and low-risk) at multiple time points (1.5 to 18 months).
- Outcome classification at 36 months.
- Statistical analysis using generalized linear mixed models and qualitative evaluation.
Main Results:
- Most parents reported no concerns in early infancy (1.5 and 3 months).
- By 6 months, parents of high-risk infants reported significantly more ASD-related and general concerns than low-risk infants.
- By 12 months, parents of high-risk infants who later developed atypically showed more ASD-related concerns than those who developed typically.
Conclusions:
- Clinicians should actively inquire about parental concerns by 6 months in high-risk infants.
- Parental identification of ASD-suggestive concerns by 12 months can facilitate earlier screening and intervention.
- Parental insights are valuable in monitoring developmental trajectories for early ASD detection.
Aim:
To examine parental concerns about children at increased familial risk (i.e. high risk) of developing autism spectrum disorder (ASD) in early infancy.
Method:
ASD-related and general parental concerns were prospectively collected for 76 infants at ages 1.5, 3, 6, 9, 12, and 18 months. Outcome classification was determined at 36 months. Analyses included generalized linear mixed models and qualitative evaluation of parental concerns in relation to risk status (high vs low risk) and outcome classification within the high-risk group (atypically developing vs typically developing) over time.
Results:
Most parents had no concerns at 1.5 (high risk 71%, low risk 87%) and 3 months (high risk 77%, low risk 86%). Beginning at 6 months, parents of high-risk infants reported more ASD-related (p<0.001) and general concerns (p=0.003) than parents of low-risk infants. Beginning at 12 months, parents of high-risk atypically developing infants reported more ASD-related concerns than parents of high-risk typically developing infants (p=0.013).
Interpretation:
Clinicians should elicit parental concerns and provide support, as parents are worried about their high-risk infants by age 6 months. Additionally, parents' abilities to identify concerns that are suggestive of ASD by age 12 months may aid in earlier screening and intervention. What this paper adds Most parents did not report concerns during early infancy. By 6 months, parents of high-risk infants reported autism spectrum disorder (ASD)-related and general concerns. By 12 months, parents of high-risk atypically developing infants identified ASD-related concerns.
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