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Updated: Nov 2, 2025

Practical Considerations in Studying Metastatic Lung Colonization in Osteosarcoma Using the Pulmonary Metastasis Assay
Published on: March 12, 2018
Trapezial Acrometastasis as the First Presentation of Occult Lung Cancer: A Case Report
Isaac Nivar1, Leighann C Panico1, Charlie Yoo1
1Department of Orthopedic Surgery, UPMC Pinnacle, Harrisburg, Pennsylvania.
Case:
Acrometastasis is extremely rare, accounting for 0.1% of all skeletal metastases. Metastases to the carpus are rarer still. This condition can be the first manifestation of an occult malignancy and generally indicates advanced disease. We present the case of a 53-year-old woman with acrometastasis of squamous cell lung cancer to the trapezium as the initial presentation of her malignancy.
Conclusion:
The presentation of acrometastasis can mimic infectious or inflammatory processes, leading to an erroneous diagnosis. Although exceptionally uncommon, it is important to consider as a differential diagnosis for a destructive hand lesion.
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