Related Experiment Video
Updated: Nov 2, 2025

Refined Murine Model of Idiopathic Pulmonary Fibrosis
Published on: June 17, 2025
Middle Lobe Syndrome Associated with Bronchial Anthracofibrosis
Ugur Gonlugur1, Tanseli Gonlugur2, Sule Ozer3
1Canakkale Onsekiz Mart University, School of Medicine, Department of Chest Diseases, 17100, Canakkale, Turkey, Orcid id: 0000-0001-8720-2788.
Bronchial anthracofibrosis, characterized by airway narrowing and dark pigmentation, can mimic other conditions in non-smokers. This case highlights the importance of considering this diagnosis and suggests cautious monitoring before invasive procedures.
Area of Science:
- Pulmonology
- Medical Case Reports
Background:
- Bronchial anthracofibrosis is defined as airway narrowing with dark pigmentation on bronchoscopy.
- It is diagnosed in the absence of a history of pneumoconiosis or smoking.
Observation:
- A 67-year-old non-smoking female presented with a two-year history of persistent cough.
- Spirometry results were normal.
- Radiological imaging revealed right middle lobe atelectasis and positron emission tomography-positive mediastinal lymph nodes.
- Bronchoscopy showed black airway discoloration and distortions.
Findings:
- The patient's presentation and bronchoscopic findings were consistent with bronchial anthracofibrosis.
- The absence of smoking or pneumoconiosis history complicated the diagnosis.
Implications:
- This case underscores the importance of considering bronchial anthracofibrosis in non-smokers presenting with relevant symptoms.
- The authors propose monthly radiological monitoring for suspected cases lacking strong indicators of malignancy or tuberculosis, prior to invasive interventions.
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