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Updated: Nov 2, 2025

Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
Recent advances in acyl radical enabled reactions between aldehydes and alkenes
Yi-Lin Liu1, Yue-Jun Ouyang1, Hongxing Zheng2
1College of Chemistry and Materials Engineering, Hunan Engineering Laboratory for Preparation Technology of Polyvinyl Alcohol (PVA) Fiber Material, Huaihua University, Huaihua, Hunan 418008, China. weiwenting@nbu.edu.cn.
Abstract:
Radical-mediated functionalization of alkenes has been emerging as an elegant and straightforward protocol to increase molecule complexity. Moreover, the abstraction of a hydrogen atom from aldehydes to afford acyl radicals has evolved as a rising star due to its high atom-economy and the ready availability of aldehydes. Considering the great influence and synthetic potential of acyl radical enabled reactions between aldehydes and alkenes, we provide a summary of the state of the art in this field with a specific emphasis on the working models and corresponding mechanisms. The discussion is divided according to the kind of alkenes and reaction type.
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