Related Experiment Video
Updated: Nov 2, 2025
Murine Myocardial Infarction Model using Permanent Ligation of Left Anterior Descending Coronary Artery
Published on: August 16, 2019
Reperfused vs. nonreperfused myocardial infarction: when to use which model
Merry L Lindsey1,2, Lisandra E de Castro Brás3, Kristine Y DeLeon-Pennell4,5
1Department of Cellular and Integrative Physiology, Center for Heart and Vascular Research, University of Nebraska Medical Center, Omaha, Nebraska.
Abstract:
There is a lack of understanding in the cardiac remodeling field regarding the use of nonreperfused myocardial infarction (MI) and reperfused MI in animal models of MI. This Perspectives summarizes the consensus of the authors regarding how to select the optimum model for your experiments and is a part of ongoing efforts to establish rigor and reproducibility in cardiac physiology research.
