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Complications associated with myocardial bridging in four children without underlying cardiac disease: a case series
Federica Brancato1, Donato Rigante1,2, Marco Piastra2,3
1Department of Life Sciences and Public Health, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
Insights
Myocardial bridging, a coronary artery anomaly, can cause symptoms like chest pain and arrhythmias in children. This study highlights its potential to be symptomatic even without other heart conditions.
Area of Science:
- Pediatric Cardiology
- Congenital Heart Anomalies
- Cardiovascular Imaging
Background:
- Myocardial bridging (MB) is a congenital coronary artery anomaly where a segment of the artery runs within the heart muscle.
- Typically considered benign, MB can cause dynamic compression during systole.
- Limited data exist on symptomatic MB in pediatric populations.
Observation:
- Four children (6-13 years) presented to a pediatric emergency department with symptomatic MB.
- Presentations included exertional chest pain and septic shock.
- No other underlying cardiac abnormalities were identified in these patients.
Findings:
- Computed tomography (CT) confirmed MB of the left anterior descending (LAD) coronary artery branches in three patients.
- Two-year follow-up was uneventful for these three.
- The fourth patient experienced ventricular fibrillation and autopsy revealed a significant intramyocardial LAD tract.
Implications:
- Symptomatic MB should be considered in the differential diagnosis for pediatric exertional chest pain.
- MB can present with serious complications, including arrhythmias, in children.
- Further investigation into pediatric MB is warranted to understand its clinical significance.
Background:
Myocardial bridging is largely considered to be a benign, symptomless congenital anomaly of the coronary arteries in which the intramyocardial coronary course is partially 'tunnelled' and leads to vessel compression during ventricular systole. There are few data regarding children.
Objective:
To report on myocardial bridging observed in children seeking medical help in the paediatric emergency room.
Case Presentation:
A series of four children aged 6-13 years with symptomatic myocardial bridging but no other underlying cardiac abnormalities is reported. They were admitted to the paediatric emergency department during 2013-2016, three with chest pain after physical activity and one with septic shock.
Results:
Heart computed tomography scan in the first three demonstrated myocardial bridging of the left anterior descendent coronary artery's branches; their 2-year follow-up was uneventful. The fourth patient presented with ventricular fibrillation 24 hours after admission and at autopsy there was an intramyocardial tract 4 cm long on the left anterior descendent coronary artery.
Conclusions:
This case series demonstrates that myocardial bridging can be symptomatic in children with no underlying cardiac disorders and should be included in the differential diagnosis of exertional chest pain and/or arrhythmias.Abbreviations: CRP, C-reactive protein; CT, computed tomography; D1, diagonal 1 artery; ECG, electrocardiogram; ED, emergency department; KD, Kawasaki disease; LAD, left anterior descending coronary artery; MB, myocardial bridging; RI, ramus intermedius artery; TN, troponin.
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