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Updated: Nov 2, 2025

Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling
Published on: April 7, 2015
Extensive right-sided infectious endocarditis due to Streptococcus pneumoniae
Patrícia Rocha1, Pedro Fernandes Rodrigues1, Ana Lima Silva2
1Internal Medicine, Centro Hospitalar do Médio Ave EPE, Vila Nova de Famalicão, Portugal.
Streptococcus pneumoniae rarely causes infectious endocarditis, often leading to aggressive illness. This case highlights a successful treatment of a 36-year-old man with ventricular septal defect and pneumococcal endocarditis.
Area of Science:
- Cardiology
- Infectious Diseases
- Pulmonology
Background:
- Infectious endocarditis caused by Streptococcus pneumoniae is uncommon.
- Cases typically present with acute, aggressive disease and high mortality rates.
Observation:
- A 36-year-old male with unrepaired ventricular septal defect presented with a 3-month history of fever, cough, and asthenia.
- Blood cultures confirmed Streptococcus pneumoniae infection.
- Echocardiography revealed large vegetations on the right ventricle.
- Thoracic CT identified septic pulmonary embolism.
Findings:
- Successful treatment involved antimicrobial therapy and surgical intervention.
- The patient experienced a favorable clinical outcome.
Implications:
- This case underscores the importance of considering rare pathogens in endocarditis.
- Prompt diagnosis and combined medical-surgical management are crucial for favorable outcomes in complex cases.
- Highlights the potential for Streptococcus pneumoniae to cause subacute, severe endocarditis in patients with congenital heart defects.
Related Concept Videos
Endocarditis I: Introduction
Endocarditis II: Clinical Features of Infective Endocarditis
Endocarditis IV: Nursing Management
Endocarditis III: Medical Management
Rheumatic Heart Disease I: Introduction
Pneumonia III: Complications and Assessment

