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Graves'-induced prothrombotic state and the risk of early-onset myocardial infarction
Meilyr Dixey1, Alice Barnes1, Fiqry Fadhlillah2
1Imperial College Healthcare NHS Trust, London, UK.
Abstract:
Hyperthyroidism represents a state of hypercoagulability and hypofibrinolysis, which predisposes an individual to the increased risk of thromboembolism. We present a case of a 25-year-old patient presenting with an acute myocardial infarction secondary to plaque rupture with thrombotic occlusion of proximal left anterior descending artery, in a patient known to have Graves' disease. She had a sudden ventricular fibrillation arrest and a precordial thump given and cardiopulmonary resuscitation started. She successfully underwent cardiac catheterisation. Subsequent thyroid function tests showed she was in active thyrotoxicosis.
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