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Edible Materials in Tissue Regeneration.

Xiaohan Su1, Caihong Xian1, Ming Gao2

  • 1School of Biomedical Engineering, Sun Yat-sen University, Shenzhen, 518057, China.

Macromolecular Bioscience
|June 12, 2021
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Edible materials like natural polysaccharides, proteins, and phenolic compounds show promise for tissue regeneration, aiding wound healing and bone repair through their bioactive properties.

Keywords:
bone regenerationedible materialstissue engineeringwound healing

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Area of Science:

  • Biomaterials Science
  • Regenerative Medicine
  • Tissue Engineering

Background:

  • Edible materials, including natural polysaccharides, phenolic compounds, and proteins, are increasingly recognized for their biocompatibility, biodegradability, and biological activity.
  • These materials offer a sustainable and accessible source for applications in regenerative medicine.
  • Their inherent properties make them suitable candidates for enhancing tissue repair processes.

Purpose of the Study:

  • To review the applications of edible materials in tissue regeneration, focusing on wound healing and bone tissue regeneration.
  • To elucidate the mechanisms underlying the therapeutic effects of edible materials in healing processes.
  • To explore the potential of edible materials as scaffolds or agents for bone repair and osteogenesis.

Main Methods:

  • Systematic review of existing literature on edible materials in tissue regeneration.
  • Analysis of the sources and bioactive properties of natural polysaccharides, phenolic compounds, and proteins.
  • Investigation of the mechanisms of action in wound healing, including hemostasis, antibacterial, anti-inflammatory, and antioxidant effects.
  • Evaluation of edible materials' roles in bone regeneration, scaffold development, and cytokine regulation.

Main Results:

  • Edible materials exhibit significant hemostatic, antibacterial, anti-inflammatory, and antioxidant properties beneficial for wound healing.
  • They can serve as effective scaffolds or delivery agents in bone tissue engineering.
  • These materials can modulate osteogenesis-related cytokines, promoting enhanced bone repair.
  • The review highlights the diverse applications and mechanisms of edible materials in regenerative medicine.

Conclusions:

  • Edible materials represent a promising class of biomaterials for advancing wound healing and bone regeneration.
  • Further research into their specific mechanisms and optimized application strategies can unlock their full therapeutic potential.
  • The sustainable and biocompatible nature of edible materials positions them as key components in future regenerative medicine strategies.