Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Transdermal Delivery of Ruxolitinib Through CO<sub>2</sub> Ablative Laser -Assisted Silk Nanovehicle System for Improved Melanocyte Recovery in Vitiligo.

Advanced healthcare materials·2026
Same author

Correction to "Magnesium Ion/Gallic Acid MOF-Laden Multifunctional Acellular Matrix Hydrogels for Diabetic Wound Healing".

ACS applied bio materials·2026
Same author

Fabrication of Multifaceted Angiogenic and Osteogenic Niches With Silk Cryogels for Orchestrating Bone Regeneration.

Advanced healthcare materials·2026
Same author

Transdermal Silk-Recombinant Collagen Nanocomplexes with Synergistic Bioactivity.

ACS biomaterials science & engineering·2026
Same author

Corrigendum to Axon guidance cue SLIT2 regulates the murine skeletal stem cell niche through sympathetic innervation.

The Journal of clinical investigation·2026
Same author

Expression of Concern for Axon guidance cue SLIT2 regulates the murine skeletal stem cell niche through sympathetic innervation.

The Journal of clinical investigation·2025

Related Experiment Video

Updated: Nov 2, 2025

Author Spotlight: Insights into the Use of Apple-Derived Cellulose Scaffolds for Bone Tissue Engineering
09:49

Author Spotlight: Insights into the Use of Apple-Derived Cellulose Scaffolds for Bone Tissue Engineering

Published on: February 23, 2024

2.1K

Silk Biomaterials for Bone Tissue Engineering.

Zhaozhao Ding1, Weinan Cheng2, Md Shipan Mia1

  • 1National Engineering Laboratory for Modern Silk and Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University, Suzhou, 215123, P. R. China.

Macromolecular Bioscience
|June 12, 2021
PubMed
Summary

Silk biomaterials show great potential for bone tissue engineering due to their biocompatibility and ability to accelerate bone regeneration. Recent advancements focus on fabrication and functionalization methods to enhance osteogenesis for future bone repair applications.

Keywords:
angiogenesisbone tissue engineeringosteogenesissilkstem cells

More Related Videos

Designing Silk-silk Protein Alloy Materials for Biomedical Applications
11:14

Designing Silk-silk Protein Alloy Materials for Biomedical Applications

Published on: August 13, 2014

18.6K
Biological Compatibility Profile on Biomaterials for Bone Regeneration
10:28

Biological Compatibility Profile on Biomaterials for Bone Regeneration

Published on: November 16, 2018

12.9K

Related Experiment Videos

Last Updated: Nov 2, 2025

Author Spotlight: Insights into the Use of Apple-Derived Cellulose Scaffolds for Bone Tissue Engineering
09:49

Author Spotlight: Insights into the Use of Apple-Derived Cellulose Scaffolds for Bone Tissue Engineering

Published on: February 23, 2024

2.1K
Designing Silk-silk Protein Alloy Materials for Biomedical Applications
11:14

Designing Silk-silk Protein Alloy Materials for Biomedical Applications

Published on: August 13, 2014

18.6K
Biological Compatibility Profile on Biomaterials for Bone Regeneration
10:28

Biological Compatibility Profile on Biomaterials for Bone Regeneration

Published on: November 16, 2018

12.9K

Area of Science:

  • Biomaterials Science
  • Regenerative Medicine
  • Tissue Engineering

Background:

  • Silk, a natural fibrous polymer, is increasingly recognized for its potential in regenerative medicine, particularly in bone tissue engineering.
  • Silk possesses favorable characteristics including biocompatibility, biodegradability, and suitable mechanical properties for bone applications.
  • Extensive in vitro and in vivo research validates silk's efficacy in promoting and accelerating bone regeneration.

Purpose of the Study:

  • To review recent progress in silk-based bone biomaterials.
  • To focus on fabrication and functionalization techniques that promote osteogenesis.
  • To identify challenges and future directions for silk in bone tissue engineering.

Main Methods:

  • Review of existing literature on silk-based materials for bone regeneration.
  • Analysis of various fabrication methods for silk scaffolds, hydrogels, and films.
  • Discussion of functionalization strategies involving bioactive factors and stem cells.

Main Results:

  • Silk-based materials are effectively processed into various forms (scaffolds, hydrogels, films) for bone regeneration.
  • Incorporation of bioactive factors and stem cells into silk matrices creates conducive osteogenic microenvironments.
  • Studies confirm silk's role in directing cell behavior and enhancing bone regeneration.

Conclusions:

  • Silk-based biomaterials represent a promising avenue for bone tissue engineering.
  • Continued research into fabrication and functionalization is crucial for optimizing silk's osteogenic potential.
  • Addressing current challenges will guide the future development of advanced silk bone materials.