Recent advances in colorimetry/fluorimetry-based dual-modal sensing technologies

Area of Science:

• Analytical Chemistry
• Materials Science
• Nanotechnology

Background:

• Dual-modal sensing technologies integrate multiple signal transduction channels to enhance analytical performance.
• Colorimetric and fluorescent signals are preferred for dual-modal sensors due to their suitability for point-of-care and real-time applications.
• Recent advances in material chemistry and nanotechnology have significantly propelled the development of dual-modal sensing.

Purpose of the Study:

• To comprehensively review colorimetric/fluorimetric dual-modal sensing methods developed in the last five years.
• To analyze the sensing methodologies and signal transduction principles of these dual-modal sensors.
• To discuss the challenges and future prospects in the field of colorimetric/fluorimetric dual-modal sensing.

Main Methods:

• Review of recent literature (last 5 years) on colorimetric/fluorimetric dual-modal sensing technologies.
• Analysis of sensing mechanisms and signal transduction pathways.
• Highlighting representative research and applications.

Main Results:

• Integration of colorimetric and fluorescent signals improves analytical efficiency, accuracy, and flexibility.
• Dual-modal sensors offer complementary and synergistic effects for diverse applications.
• Significant progress has been made in developing sophisticated colorimetric/fluorimetric dual-modal sensing strategies.

Conclusions:

• Colorimetric/fluorimetric dual-modal sensing technologies offer a powerful platform for disease diagnosis, environmental monitoring, and food safety.
• Further research is needed to address current challenges and unlock the full potential of these advanced sensing systems.
• The synergistic combination of colorimetric and fluorescent outputs provides enhanced analytical capabilities beyond single-modal approaches.