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Transient Middle Cerebral Artery Occlusion Model of Neonatal Stroke in P10 Rats
Published on: April 21, 2017
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[Challenges and advances in paediatric arterial ischaemic stroke]
Julie Brix Bindslev1, Thomas Truelsen, Mette Gyhrs
1jbbindslev@gmail.com.
Ugeskrift for Laeger
|June 14, 2021
Summary
Pediatric arterial ischemic stroke affects over half of children, often with delayed diagnosis. Implementing a systematic pathway can improve recognition and treatment for better outcomes in childhood stroke.
Area of Science:
- Pediatric Neurology
- Neurovascular Diseases
- Stroke Medicine
Background:
- Neurological sequelae affect over 50% of children diagnosed with arterial ischemic stroke (AIS).
- Current diagnostic timelines for pediatric stroke frequently exceed 24 hours, delaying critical interventions.
- Access to hyperacute recanalisation therapies remains limited in the pediatric population.
Purpose of the Study:
- To review clinical presentations, risk factors, and treatment strategies for pediatric ischemic stroke.
- To present the experience and outcomes of a systematic pediatric stroke pathway implemented in Eastern Denmark since 2017.
Main Methods:
- Systematic review of clinical presentations, risk factors, and treatments for pediatric ischemic stroke.
- Description of a implemented systematic pediatric stroke pathway in Eastern Denmark.
Main Results:
- Neurological sequelae are prevalent in over 50% of pediatric AIS cases.
- Diagnostic delays are common, exceeding 24 hours in many instances.
- The implemented pathway aims to expedite recognition and treatment.
Conclusions:
- Early recognition and prompt treatment are crucial for improving outcomes in pediatric stroke.
- Systematic pathways are essential for optimizing the management of childhood arterial ischemic stroke.
- The Danish pathway demonstrates a structured approach to enhancing pediatric stroke care.
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