Related Experiment Video

Updated: Nov 2, 2025

A Method for High Fidelity Optogenetic Control of Individual Pyramidal Neurons In vivo
13:44

A Method for High Fidelity Optogenetic Control of Individual Pyramidal Neurons In vivo

Published on: September 2, 2013

19.3K

Optogenetic control of calcium influx in mammalian cells

Yi-Tsang Lee1, Rui Chen1, Yubin Zhou1

  • 1Center for Translational Cancer Research, Institute of Biosciences and Technology, Texas A&M University, Houston, TX, United States.

Methods in Enzymology
|June 14, 2021
PubMed

Keywords:
ActuatorsCRISPRCalcium signalingIon channelORAI1OptogeneticsProtein engineeringSTIM1Synthetic biologyTranscriptional programming

More Related Videos

Optical Control of a Neuronal Protein Using a Genetically Encoded Unnatural Amino Acid in Neurons08:20

Optical Control of a Neuronal Protein Using a Genetically Encoded Unnatural Amino Acid in Neurons

Published on: March 28, 2016

8.1K
Dissection of Local Ca2+ Signals in Cultured Cells by Membrane-targeted Ca2+ Indicators11:33

Dissection of Local Ca2+ Signals in Cultured Cells by Membrane-targeted Ca2+ Indicators

Published on: March 22, 2019

9.2K

Related Concept Videos

Feedback Regulation of Calcium Concentration01:27

Feedback Regulation of Calcium Concentration

Calcium is an essential signaling molecule required for various cellular functions. Calcium pumps and ion channels on cell and organellar membranes, such as those on the endoplasmic reticulum (ER), regulate calcium concentrations inside the cell. They remain closed, keeping the cytosolic calcium levels low at a resting state.
Various transmembrane receptors, such as G protein-coupled receptors (GPCRs), elicit a response to extracellular signals by increasing cytosolic calcium. Activated GPCRs...
3.6K