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Esophageal web in Plummer-Vinson syndrome
H Okamura1, S Tsutsumi, S Inaki
1Department of Otolaryngology, School of Medicine, Ehime University, Japan.
The Laryngoscope
|September 1, 1988
Summary
Plummer-Vinson syndrome involves an esophageal web, potentially caused by inflammation and healing. Iron deficiency anemia may reduce swallowing power, leading to dysphagia.
Area of Science:
- Gastroenterology
- Pathophysiology
Background:
- Plummer-Vinson syndrome is characterized by an esophageal web and dysphagia.
- Esophagography commonly identifies cervical esophageal webs.
Purpose of the Study:
- To investigate the pathogenesis of esophageal webs in Plummer-Vinson syndrome.
- To determine the cause of dysphagia in this condition.
Main Methods:
- Radiographic, endoscopic, manometric, and histological examinations were employed.
- The study analyzed the formation of esophageal webs and swallowing function.
Main Results:
- Esophageal webs may form from restricted esophageal wall dilation due to inflammation and healing.
- Reduced swallowing power is a likely cause of dysphagia.
Conclusions:
- Iron deficiency anemia is implicated in the histological changes and decreased swallowing power.
- Understanding the pathogenesis aids in managing Plummer-Vinson syndrome symptoms.