Related Experiment Video
Updated: Nov 2, 2025

A Data-Driven Approach to Quantifying Immune States in Sepsis
Published on: February 7, 2025
Stationary distribution and density function expression for a stochastic SIQRS epidemic model with temporary immunity
Baoquan Zhou1, Daqing Jiang1,2, Yucong Dai1
1College of Science, China University of Petroleum (East China), Qingdao, 266580 People's Republic of China.
This study introduces a stochastic epidemic model incorporating quarantine and temporary immunity. It establishes conditions for disease persistence, providing a unique stationary distribution for epidemiological dynamics.
Area of Science:
- Mathematical epidemiology
- Stochastic modeling
- Dynamical systems theory
Background:
- Previous models like susceptible-infected-recovered-susceptible (SIRS) lack realistic quarantine and stochasticity.
- Temporary immunity after recovery is a key factor in disease dynamics.
- Logistic growth influences population dynamics in epidemic models.
Purpose of the Study:
- To analyze a stochastic susceptible-infected-quarantined-recovered-susceptible (SIQRS) epidemic model with temporary immunity.
- To determine the conditions for disease persistence and the existence of a unique ergodic stationary distribution.
- To derive the explicit expression for the stationary distribution's probability density function.
Main Methods:
- Application of Khas'minskii theory and Lyapunov function approach.
- Construction of a critical value related to the basic reproduction number.
- Development of solving theories for a four-dimensional Fokker-Planck equation.
- Analysis of stochastic differential equations and ergodic theory.
Main Results:
- A critical value is established, determining disease persistence.
- A unique ergodic stationary distribution exists when .
- The explicit density function of the stationary distribution is obtained under .
- Numerical simulations validate the theoretical findings.
Conclusions:
- The existence of a unique stationary distribution reveals disease persistence dynamics.
- The model provides insights into the interplay of quarantine, temporary immunity, and stochasticity.
- Findings contribute to understanding disease spread in both epidemiological and statistical contexts.
Related Concept Videos
Survival Curves
The Kaplan-Meier estimator is the most common method for constructing survival curves. This...
Parametric Survival Analysis: Weibull and Exponential Methods
Weibull Distribution
The Weibull distribution is a flexible model used in parametric survival analysis. It can handle both increasing and decreasing hazard rates, depending on its shape parameter...
Steps in Outbreak Investigation
Uniform Distribution
Two essential properties of this distribution are
Poisson Probability Distribution
The...
Two-Compartment Open Model: IV Infusion
The model illustrates the decrease in plasma drug concentration from the central compartment with a specific equation. It shows that under steady-state conditions, the drug's input rate...

